---
title: "The NIH Human Microbiome Project"
description: "The Human Microbiome Project (HMP), funded as an initiative of the NIH Roadmap for Biomedical Research ( http://nihroadmap.nih.gov ), is a multi-component community resource. The goals of the HMP are: (1) to take advantage of new, high-throughput technologies to characterize the human microbiome more fully by…"
datePublished: "2009-12-01"
lastmod: "2026-10-08T09:14:47+00:00"
authors:
  - "Jane Peterson"
  - "Susan Garges"
  - "Maria Giovanni"
  - "Pamela McInnes"
  - "Lu Wang"
  - "Jeffery A. Schloss"
  - "Vivien Bonazzi"
  - "Jean E. McEwen"
  - "Kris A. Wetterstrand"
  - "Carolyn Deal"
  - "Carl C. Baker"
  - "Valentina Di Francesco"
  - "T. Kevin Howcroft"
  - "Robert W. Karp"
  - "R. Dwayne Lunsford"
  - "Christopher R. Wellington"
  - "Tsegahiwot Belachew"
  - "Michael Wright"
  - "Christina Giblin"
  - "Hagit David"
  - "Melody Mills"
  - "Rachelle Salomon"
  - "Christopher Mullins"
  - "Beena Akolkar"
  - "Lisa Begg"
  - "Cindy Davis"
  - "Lindsey Grandison"
  - "Michael Humble"
  - "Jag Khalsa"
  - "A. Roger Little"
  - "Hannah Peavy"
  - "Carol Pontzer"
  - "Matthew Portnoy"
  - "Michael H. Sayre"
  - "Pamela Starke-Reed"
  - "Samir Zakhari"
  - "Jennifer Read"
  - "Bracie Watson"
  - "Mark Guyer"
journal: "Genome Research"
publisher: "Cold Spring Harbor Laboratory"
doi: "10.1101/gr.096651.109"
publicationType: "journal-article"
schemaType: "ScholarlyArticle"
volume: "19"
issue: "12"
pages: "2317-2323"
language: "en-GB"
slug: "10.1101-gr.096651.109"
---

# The NIH Human Microbiome Project

**Authors:** Jane Peterson, Susan Garges, Maria Giovanni, Pamela McInnes, Lu Wang, Jeffery A. Schloss, Vivien Bonazzi, Jean E. McEwen, Kris A. Wetterstrand, Carolyn Deal, Carl C. Baker, Valentina Di Francesco, T. Kevin Howcroft, Robert W. Karp, R. Dwayne Lunsford, Christopher R. Wellington, Tsegahiwot Belachew, Michael Wright, Christina Giblin, Hagit David, Melody Mills, Rachelle Salomon, Christopher Mullins, Beena Akolkar, Lisa Begg, Cindy Davis, Lindsey Grandison, Michael Humble, Jag Khalsa, A. Roger Little, Hannah Peavy, Carol Pontzer, Matthew Portnoy, Michael H. Sayre, Pamela Starke-Reed, Samir Zakhari, Jennifer Read, Bracie Watson, Mark Guyer  
**Journal:** Genome Research  
**Publisher:** Cold Spring Harbor Laboratory  
**Published:** 2009-12-01  
**Volume:** 19  
**Issue:** 12  
**Pages:** 2317-2323  
**DOI:** [10.1101/gr.096651.109](https://dx.doi.org/10.1101/gr.096651.109)

## Abstract

The Human Microbiome Project (HMP), funded as an initiative of the NIH Roadmap for Biomedical Research ( http://nihroadmap.nih.gov ), is a multi-component community resource. The goals of the HMP are: (1) to take advantage of new, high-throughput technologies to characterize the human microbiome more fully by studying samples from multiple body sites from each of at least 250 “normal” volunteers; (2) to determine whether there are associations between changes in the microbiome and health/disease by studying several different medical conditions; and (3) to provide both a standardized data resource and new technological approaches to enable such studies to be undertaken broadly in the scientific community. The ethical, legal, and social implications of such research are being systematically studied as well. The ultimate objective of the HMP is to demonstrate that there are opportunities to improve human health through monitoring or manipulation of the human microbiome. The history and implementation of this new program are described here.

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